A UPS cargo plane crashed and burst into flames on Tuesday while taking off from Louisville’s Muhammad Ali International Airport.
7 Dead and 11 Injured
Authorities said seven people have died and 11 have been injured due to the UPS plane crash, the Associated Press reported. The officer also added that all departing flights have been canceled after the crash. The Federal Aviation Administration said the aircraft was departing for Honolulu around 5:15 pm when it went down.
Insane footage posted on Instagram which appears the show the crash earlier of UPS Flight 2976, a McDonnell Douglas MD-11 Cargo Plane operated by UPS Airlines, during takeoff at Muhammad Ali International Airport in Louisville, Kentucky. Prior to the crash, a clear fire can been… pic.twitter.com/RpKJoNQekW
— OSINTdefender (@sentdefender) November 4, 2025
Viral Video of UPS Cargo Plane
A video showed flames on the left wing and a trail of smoke as the plane briefly lifted off before crashing and erupting into a massive fireball. Several buildings were ablaze following the crash of the plane. Three crew members were on board.
All 3 Crew Members Died
UPS said the plane had three crew members on board, and federal officials indicated all were feared dead, Reuters reported. Louisville Metro Emergency Services ordered everyone within five miles (8 km) of the airport to shelter in place.
“There are multiple injuries, and the fire is still burning. There are many road closures in the area please avoid the scene,” Louisville Mayor Craig Greenberg said in a post shortly before 7 p.m. ET (0000 GMT).
Investigation to Determine Exact Crash Cause
The National Transportation Safety Board, which said it would be leading an investigation into the accident, was sending a team to the scene. NTSB investigations typically take 12 to 24 months to establish a probable cause and issue safety recommendations.
Louisville’s airport, which hosts UPS Worldport, the company’s global air hub and largest package-handling facility, closed the airfield after the incident.
The crash is expected to disrupt UPS deliveries, including for major clients such as Amazon, Walmart, and the US Postal Service. Walmart and Amazon did not immediately respond to requests for comment.
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The largest package handling facility of UPS is in Louisville. It employs thousands and has 300 daily flights and sorts more than 400,000 packages per hour. Records from the FAA indicated that the MD-11 freighter that crashed was 34 years old.
Boeing, which ended the MD-11 program after its merger with McDonnell Douglas, said it was concerned for all those affected and would provide technical support for the investigation.
