Feb 24, 2025
Scientists Develop 3D Microscope to Map Cell Molecules
Researchers have invented a groundbreaking 3D microscope that images molecules within cells with unprecedented precision
Indian researchers at MBL developed a hybrid microscope that captures 3D protein orientation and molecular location
The microscope uses polarized fluorescence technology in combination with a dual-view light sheet microscope (diSPIM) for high-resolution imaging
It captures 3D protein orientation dynamics, allowing researchers to decipher molecular interactions and cellular processes
The technology breaks imaging barriers for molecules in dividing cells, giving clearer views of cellular processes
The research began in 2016 with researchers Hari Shroff and Abhishek Kumar, who created the bespoke diSPIM microscope
Researchers hope to speed up imaging for live cell observations and create new fluorescent probes for wider use
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