Monkeypox is caused by the monkeypox virus, a member of the Orthopoxvirus family

Chickenpox is caused by the varicella-zoster virus, part of the herpesvirus family

Monkeypox symptoms include fever, headache, and a rash that turns into pustules. Monkeypox rash is typically more severe and starts on the face and extremities

Chickenpox mainly causes an itchy, blister-like rash

Monkeypox spreads through close contact with an infected person or animal, or through contaminated materials

Chickenpox is highly contagious and spreads through respiratory droplets, making it easier to catch from an infected person

The rash in monkeypox usually begins on the face and then spreads to the rest of the body, including palms and soles

Chickenpox rash generally starts on the chest and back, then spreads to the rest of the body

Monkeypox is often more severe than chickenpox, with a higher risk of complications like pneumonia and sepsis

Chickenpox, while usually mild, can lead to serious issues like bacterial infections and shingles later in life

The smallpox vaccine provides protection against monkeypox

The varicella vaccine  provides protection against Chickenpox