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Study on mice suggests childhood diet has lifelong impact

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California [US], February 6 (ANI): A new study in mice suggests that eating too much fat and sugar as a child can alter one’s microbiome for life, even if you later learn to eat healthier.
The study by UC Riverside researchers is one of the first to show a significant decrease in the total number and diversity of gut bacteria in mature mice fed an unhealthy diet as juveniles.
“We studied mice, but the effect we observed is equivalent to kids having a Western diet, high in fat and sugar and their gut microbiome still being affected up to six years after puberty,” explained UCR evolutionary physiologist Theodore Garland.
A paper describing the study has recently been published in the Journal of Experimental Biology.
The microbiome refers to all the bacteria as well as fungi, parasites, and viruses that live on and inside a human or animal. Most of these microorganisms are found in the intestines, and most of them are helpful, stimulating the immune system, breaking down food, and helping synthesize key vitamins.
In a healthy body, there is a balance of pathogenic and beneficial organisms. However, if the balance is disturbed, either through the use of antibiotics, illness, or an unhealthy diet, the body could become susceptible to disease.
In this study, Garland’s team looked for impacts on the microbiome after dividing their mice into four groups: half fed the standard, ‘healthy’ diet, half-fed the less healthy ‘Western’ diet, half with access to a running wheel for exercise, and a half without.
After three weeks spent on these diets, all mice were returned to a standard diet and no exercise, which is normally how mice are kept in a laboratory. At the 14-week mark, the team examined the diversity and abundance of bacteria in the animals.
They found that the quantity of bacteria such as Muribaculum intestinale was significantly reduced in the Western diet group. This type of bacteria is involved in carbohydrate metabolism.
Analysis also showed that the gut bacteria are sensitive to the amount of exercise the mice got. Muribaculum bacteria increased in mice fed a standard diet who had access to a running wheel and decreased in mice on a high-fat diet whether they had exercise or not.
Researchers believe this species of bacteria, and the family of bacteria that it belongs to, might influence the amount of energy available to its host. Research continues into other functions that this type of bacteria may have.
One other effect of note was the increase in a highly similar bacteria species that were enriched after five weeks of treadmill training in a study by other researchers, suggesting that exercise alone may increase its presence.
Overall, the UCR researchers found that early-life Western diet had more long-lasting effects on the microbiome than did early-life exercise.
Garland’s team would like to repeat this experiment and take samples at additional points in time, to better understand when the changes in mouse microbiomes first appear, and whether they extend into even later phases of life.
Regardless of when the effects first appear, however, the researchers say it’s significant that they were observed so long after changing the diet, and then changing it back.
The takeaway, Garland said, is essentially, “You are not only what you eat, but what you ate as a child!” (ANI)

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Lifestyle & Entertainment

JACQUELINE SHARES SELFIE OF HERSELF RESTING AT HOME, URGES PEOPLE TO STAY SAFE

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MUMBAI: Back to spending time at home amid the coronavirus-induced lockdown, Bollywood star Jacqueline Fernandez on Wednesday posted a stunning monochromatic photo from her home, urging people to stay safe.The ‘Kick’ actor posted a gorgeous picture on Instagram of herself resting in a chair. The picture shows the ‘Aladdin’ actor in a thigh-length jumpsuit and a messy bun. She is seen seated in her room taking rest during the lockdown.

Fernandez captioned the post as “Back to this.. stay safe everyone (and added a joined hands emoticon).”

Celebrity followers including Vaani Kapoor and more than 4.9 lakh fans liked the post on the photo-sharing platform, while many chimed into the comments section and dropped red heart and fire emoticons as they adored the lovable photo.

Of late, the actor has been quite active on social media and has been updating fans on her activities by posting pictures and videos. Earlier, the ‘Brothers’ star shared a picture after her physiotherapy. She shared a photo that showcased the cupping marks down her back when posing for a mirror selfie.Currently, the actor is spending time with her kittens at her home amid the coronavirus-induced lockdown.Meanwhile, 58,924 new COVID-19 cases were reported in Maharashtra in the last 24 hours, according to the state health ministry. As many as 52,412 people recovered in the said period and 351 died. The total case tally reached 38,98,262 while the death toll reached 60,824.

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ALL NEW AMAZON ORIGINAL ‘LOL – HASSE TOH PHASSE’ TRAILER UNVEILED

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MUMBAI: Amazon Prime Video, unveiled the official trailer of the all-new Amazon Original Series ‘LOL- Hasse Toh Phasse’. This local edition of the International Amazon Original Series LOL, will unite an eclectic group of comedians who have left their own indelible mark on India’s comedy landscape. Aadar Malik, Aakash Gupta, Aditi Mittal, Ankita Shrivastav, Cyrus Broacha, Gaurav Gera, Kusha Kapila, Mallika Dua, Sunil Grover and Suresh Menon, under the vigilant watch of hosts Arshad Warsi and Boman Irani will face their toughest challenge yet!

Perhaps for the first time, it’s not just their sense of humor but also their endurance which will be tested as they battle it out for six consecutive hours, to make the others in the house laugh, while maintaining a poker face themselves! The goal is to be the last one laughing in the room, and the person who keeps a straight face the longest will eventually win the game. Prime Members in Indian and across 240 countries and territories can binge-watch the show starting 30th April, 2021 exclusively on Amazon Prime Video.

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MADHURI DIXIT PERFORMS TO VIRAL ‘BAJRE DA SITTA’ TREND

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NEW DELHI: Bollywood star Madhuri Dixit recently became the latest addition to the viral ‘Bajre Da Sitta’ trend. The actor shared a gorgeous video of her performing to the popular song and giving priceless expressions.Madhuri took to her Instagram handle and shared a short clip in which she performed the viral song, flaunting her pre and post glow up looks. She captioned the post as, “On trend with #BajreDaSitta.” In the video shared by the 53-year-old actor, she could be seen lip-syncing to the song while sitting in her green room right before her makeover. Later in the clip, after the star’s dramatic transformation, she is seen clad in a light and dark pink lehenga. Madhuri also wore drop diamond earrings and a necklace, with her hair tied into a bun.

Meanwhile, on the work front, the ‘Dhak-Dhak’ girl of Bollywood will be debuting in the digital world through the suspenseful family drama series by Netflix titled ‘Finding Anamika’. The plot of the series revolves around the story of a global superstar, wife, and mom who suddenly vanishes without a trace. As police and loved ones search for answers to her disappearance, her perfectly crafted facade is stripped away, revealing hidden truths and painful lies in the life of an iconic actress. 

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AYUSHMANN CELEBRATES DAUGHTER VARUSHKA’ BIRTHDAY WITH A THROWBACK PICTURE

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NEW DELHI: Bollywood actor Ayushmann Khurrana, on Wednesday celebrated his daughter Varushka Khurrana’s 7th birthday by sharing an endearing post of her on social media.The ‘Dum Laga Ke Haisha’ actor took to his Instagram handle and shared a throwback picture of his baby girl from their last trip to the Bahamas, before the COVID pandemic in 2020. Along with it, he penned an endearing caption that read, “Happy birthday little one. The most diligent one in the family. A voracious reader and a disciplined learner. How have you become like that? That too so early in life. You need to chill ok. Always be true to this pic. This was our last international trip. Jan 2020. Nassau. Bahamas.”

Varushka’s mother Tahira Kashyap also shared a heartfelt note for the birthday girl with a happy picture from their lowkey celebration at their residence.She wrote, “Given the circumstances I know seeing the world upside down makes more sense! Happy birthday little one, this is the second consecutive birthday in a lockdown, really wish the world becomes normal so that you can share the small pleasures of a broken tooth and a bruised knee with your friends! Love you with all my being.”The picture shared by Tahira captured Varushka laughing out loud at their plush balcony while she is held upside down, surrounded by colourful balloons.

Meanwhile, Ayushmann, who made his Bollywood debut with the 2012 film ‘Vicky Donor’, has delivered a string of hits in the past couple of years. He currently has many upcoming projects in his kitty including ‘Anek’, ‘Chandigarh Kare Aashiqui’ and ‘Doctor G’.Ayushmann was last seen in Shoojit Sircar’s ‘Gulabo Sitabo’, alongside Amitabh Bachchan.

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SALMAN KHAN’S ‘RADHE’ CONFIRMED FOR MULTIPLE PLATFORMS RELEASE ON EID

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Keeping up with the promise of an Eid release, Bollywood superstar Salman Khan’s movie ‘Radhe: Your Most Wanted Bhai’ is all set to make it to the theatres and digital platforms on May 13. The trailer of the film is slated to drop tomorrow.

The digital release of ‘Radhe: Your Most Wanted Bhai’, however, won’t be available for free. The makers have taken the pay-per-view route, which means that the audience will have to pay a certain amount to watch the movie at their homes. This would not be a part of their subscription to OTT platforms. The makers of the film, on Wednesday, shared the mega release plan on their Instagram handle, along with a poster of the upcoming movie. They wrote, “The perfect Eid celebration! #Radhe: Your Most Wanted Bhai, releasing simultaneously on multiple platforms worldwide. #RadheThisEid.”

Film critic and movie trade analyst Taran Adarsh also confirmed the same on his Twitter handle by tweeting, “#RADHE IN CINEMAS AND DIGITAL MEDIUMS ON SAME DAY… #SalmanKhan’s #Radhe will release simultaneously in cinemas and digital mediums [pay per view] on 13 May 2021… Trailer drops tomorrow.”

ZEE Studios will be the first studio in India to be adopting a multi-format release worldwide. Speaking on this Shariq Patel, CBO, Zee Studios shared, “The ongoing pandemic forced us to innovate, and we are proud to be the first to embark upon this new distribution strategy. While we all love to catch the latest movies at the nearest theatres, we realized we’d be doing a disservice to Salman’s fans nationwide if we aren’t able to release theatrically in all Indian states. We sensed the need for a pay-per-view solution along with theatres, which gives the consumers flexibility and convenience of viewing the film.”

He further continued, “There cannot be a better film than Radhe to offer the audiences who’ve been waiting for an out and out entertainer for over a year now. Radhe continues our network’s deep relationship with Salman Khan and we are looking to release the film in over 40 countries including theatrical release in major overseas markets.”Salman Khan Films’ spokesperson added, “It’s imperative that we all come together and think of out-of-the-box solutions for cinema as an industry during the current pandemic situation. We will support the theatre owners by releasing the film in as many theatres as we can, keeping in line with the rules and protocols laid down by the government. But, considering the guidelines and safety measures, we also need to devise ways to ensure that the film reaches all of our audience. We don’t want to deny the audience the choice of entertainment in the comfort of their homes during these times.”

The film will be released on ZEE’s pay-per-view service ZEEPlex which rests on India’s leading OTT platform ZEE5 and also on all leading DTH operators. The actor, along with his studio partner Zee Studios, have opted for this hybrid release model given the rise in coronavirus cases across the country.‘Radhe: Your Most Wanted Bhai’ will also have a theatrical release and will be available in theaters in all Indian states where the theaters are operational as per COVID protocols. A wide international theatrical release targeting 40 countries across all international territories is also being planned. It will be the first Bollywood film to release theatrically in the UK since the lockdown last year.The action flick by the Yash Raj Films banner, directed by Prabhudeva, was earlier scheduled to release on Eid 2020, but it could not see the light of the day due to the closing of film theatres owing to coronavirus-induced lockdown.

The movie will see Salman Khan romancing Disha Patani. The flick also features Jackie Shroff and Randeep Hooda. ‘Radhe’ is co-produced by Salman Khan, Sohail Khan, and Atul Agnihotri under the banners Salman Khan Films, in association with Zee Studios, Sohail Khan Productions, and Reel Life Production.

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OSCARS ATTENDEES WILL NOT WEAR FACE MASKS DURING CEREMONY

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WASHINGTON : The 2021 Oscars won’t make face masks a requirement during its live ceremony, which is scheduled to take place this Sunday.

As per Variety, the Academy is not asking Oscar attendees to wear face masks while cameras will rolling during the live ceremony. The news was announced on Monday morning during a Zoom meeting with Academy representatives and nominees, and studio and personal publicists. Because the ceremony—being held at Union Station in downtown Los Angeles—is being treated as a TV/film production, masks are not required for people on camera, an Academy staffer explained.

However, when guests are not on camera, they are being asked to wear masks. Oscars co- producer Steven Soderbergh remained mum on face-mask protocol during a press conference with co-producers Jesse Collins and Stacey Sher. He said on Saturday that masks would play “a very important role in the story”. “If that’s cryptic, it’s meant to be,” he added. “That topic is very central to the narrative.”

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