Washington [US], February 20 (ANI): A study led by a team of scientists from the University of Calgary in Canada and the University of Liverpool in the UK sequenced the genome of a Capuchin monkey to uncover new hereditary hints about the evolution of the breed’s long life expectancy and enormous minds.
Through the findings published in the American journal PNAS, Professor Joao Pedro De Magalhaes, who researches ageing at the University of Liverpool explained, “Capuchins have the largest relative brain size of any monkey and can live past the age of 50, despite their small size, but their genetic underpinnings had remained unexplored until now.”
The researchers developed and annotated a reference assembly for white-faced capuchin monkeys (Cebus imitator) to explore the evolution of these traits.
Through a comparative genomics approach spanning a wide diversity of mammals, they identified genes under evolutionary selection associated with longevity and brain development.
“We found signatures of positive selection on genes underlying both traits, which helps us to better understand how such traits evolve. In addition, we found evidence of genetic adaptation to drought and seasonal environments by looking at populations of capuchins from a rainforest and a seasonal dry forest,” said senior author and Canada Research Chair Amanda Melin who has studied capuchin monkey behaviour and genetics for almost 20 years.
The researchers identified genes associated with DNA damage response, metabolism, cell cycle, and insulin signalling. Damage to the DNA is thought to be a major contributor to ageing and previous studies by Professor de Magalhaes and others have shown that genes involved in DNA damage responses exhibit longevity-specific selection patterns in mammals.
“Of course, because ageing-related genes often play multiple roles it is impossible to be sure whether selection in these genes is related to ageing or to other life-history traits, like growth rates and developmental times, that in turn correlate with longevity,” said Professor De Magalhaes.
“Although we should be cautious about the biological significance of our findings, it is tempting to speculate that, like in other species, changes to specific ageing-related genes or pathways, could contribute to the longevity of capuchins,” he added.
The team’s insights were made possible thanks to the development of a new technique to isolate DNA more efficiently from primate faeces.
FecalFACS utilises an existing technique that has been developed to separate cells types in body fluids – for example, to separate different cell types in blood for cancer research – and applies it to primate faecal samples.
“This is a major breakthrough because the typical way to extract DNA from faeces results in about 95-99 per cent of the DNA coming from gut microbes and food items. A lot of money has been spent sequencing genomes from different organisms than the mammals we’re actually trying to study.
Because of this, when wildlife biologists have required entire genomes, they have had to rely on more pure sources of DNA, like blood, saliva, or tissue – but as you can imagine, those are very hard to come by when studying endangered animals,” explained the study’s lead author, Dr Joseph Orkin, who completed work on this project as a postdoctoral scholar at the University of Calgary, and in his present location at Universitat Pompeu Fabra-CSIC in Barcelona.
“FecalFACS finally provides a way to sequence whole genomes from free-ranging mammals using readily available, non-invasive samples, which could really help future conservation efforts,” he added. (ANI)
The Daily Guardian is now on Telegram. Click here to join our channel (@thedailyguardian) and stay updated with the latest headlines.
For the latest news Download The Daily Guardian App.
ANGELINA JOLIE REIGNITES REUNION RUMOURS WITH EX-HUSBAND
WASHINGTON: after the Bennifer reunion, seems like a new reunion couple is going to make headlines soon as Oscar-winning actor angelina Jolie was spotted leaving her ex-husband Jonny Lee Miller’s apartment on Friday night. Page Six reported on Saturday that on the night of Friday, June 11, Angelina Jolie was clicked entering and exiting an apartment complex in Brooklyn, New York, where her first ex-husband Jonny Lee Miller resides. The 46-year-old star was clad in a long tan trench coat and face mask. in the pictures, she is seen entering the entrance of the building carrying a Louis Vuitton purse and a bottle of Peter Michael wine, which typically cost a couple of hundred dollars. Page Six reported that Jolie left the uSD 3 million home of her ex after three hours, around 10:30 p.m.
PREITY ZINTA HAPPY TO SEE PEOPLE GETTING BACK TO NORMAL
MUMBAI: Actor Preity Zinta on Sunday expressed happiness on seeing people resuming to their pre-pandemic routines. Preity is currently staying with her husband Gene Goodenough in the USA, where half of all adults are now fully vaccinated against Covid-19. Taking to Instagram, Preity shared a video of people hanging out with each other.
“Feels awesome to see people out and about enjoying each other’s company after months of being locked in their homes. Of course it helps that most of the people have been vaccinated ! Here’s to life getting back to normal and people enjoying the simple things in life,” she wrote.
Reacting to the video, actor Diana Penty commented: “Pheww…normalcy.” Preity had taken a social media break for a while. Only a few days ago, she ended her digital detox. “Best way to come back after a digital detox — a throwback picture from a few days ago when we went out to dinner after 18 months. The only thing constant in life is Change and here’s to embracing it while trying to social distance #Ting,” Preity had written.
SHAH RUKH RESPONDS TO HIDDLESTON’S APPRECIATION FOR HIM
MUMBAI: Superstar Shah Rukh Khan on Friday, responded to actor Tom Hiddleston’s recent appreciation for him while promoting the Marvel Cinematic universe show ‘Loki’, during which the latter gushed about the former.
Thanking Tom, the actor tweeted, “You are kind, God of Mischief… hope there’s no mischief behind this claim though. Lots of love Tom and can’t wait to binge Loki!!! Starting now- Ep 1!”
‘Loki’, which recently premiered on an OTT platform and has had MCu fans going gaga over it. in the promotional video posted on June 8, Tom seemed to be an avid SRK fan while playing the Word association game.
In it, he took Shah Rukh’s name when asked about his first thought on india. Later, when he was asked about bollywood, he asked back, “am i allowed to say Shah Rukh Khan again? Shah Rukh Khan again!”
The 40-year-old actor also revealed that he had a special connection with the city of Chennai. “My akka (elder sister) lives there. She used to live there. and i have been there a few times. Chennai is great,” Hiddleston said in the video.Though a huge global icon himself Tom is clearly one of Shah Rukh’s admirers since bollywood’s King Khan has a huge fan base all across the world.
In india, the first episode of ‘Loki’ was released on Wednesday. along with Tom, the show also stars Owen Wilson and follows the adventures of Loki after he was set loose during the events of the time heist in ‘Avengers: Endgame’.
AKSHAY KUMAR RECALLS DEFEATING ‘ THE UNDERTAKER’ IN REEL LIFE
MUMBAI: Akshay Kumar shared a memory of him defeating ‘The Undertaker’ in ‘Khiladiyon Ka Khiladi’. For the unversed, Akshay fought the doppelganger of the popular veteran American wrestler Mark William Calaway, popularly known as The Undertaker, in the film. Many people assumed that the real Undertaker had made his Bollywood debut opposite Akshay but it was wrester Brian Lee who essayed The Undertaker’s role. Akshay shared a hilarious meme on Instagram.
“Raise your hand if you have defeated The Undertaker,” the meme read. The meme has images of Akshay along with popular wrestlers, including Triple H and Brock Lesnar. “A hilarious note to mark 25 years to the release of #KhiladiyonKaKhiladi tomorrow! A fun fact though: it was wrestler Brian Lee who played The Undertaker in film,” Akshay quipped.
MOST DESIRABLE BOLLYWOOD ACTORS TODAY
ADITYA ROY KAPUR
Known to be Bollywood’s favourite boy, Aditya Roy Kapur has never really failed to surprise us with his films and most importantly, physical transformations that he undergoes for each character. After being hailed as the new big action star post the success of ‘Malang’, Aditya is now gearing up for the highly anticipated ‘Om’. Over the years, Roy Kapur has won hearts with different shades of acting in his journey including comedy, romance, drama and action. Being in the industry for over 11 years now, the good looking and talented actor continues to receive the same amount of love from fans all across.
Hailed as an action movie star who’s as effortless when it comes to romancing his leading lady in a film, Tiger Shroff has delivered back to back hits ever since his big debut with ‘Heropanti’ in 2014. Having an exciting lineup of films, Tiger will be next seen in
‘Heropanti 2’, ‘Rambo’ and ‘Ganpath Part I’. Over the years, Tiger has earned himself a huge fan base, thanks to his acting talent and that droolworthy chiseled body.
Think cool, smart, funny, talented and a favourite of the masses, and the first name that really strikes in is that of Varun Dhawan. Rightly called the wholesome packed of entertainment, Varun Dhawan is undoubtedly one of the most loved movie stars in the industry today. Last seen in ‘Coolie No. 1’, the actor never fails to surprise us with his power-packed performances.
Hailing from the first film family of Bollywood, Ranbir Kapoor is Kapoor Khandaan’s gift to the Hindi film industry. The supremely talented actor has time and again wowed the audiences and the critics with his natural yet class apart acting chops. Next to be seen in the highly anticipated Ayan Mukerji directorial ‘Brahmastra’ alongside megastar Amitabh Bachchan and Alia Bhatt, Ranbir yet again earned himself a Filmfare Award for his breakthrough performance in his last release ‘Sanju’. Said to be director’s favourite, this Kapoor lad has his own ways of charming us with his incredible talent and to die for looks.
KANGANA BACK TO HER HORSEBACK RIDING SESSION
MUMBAI: It must be a productive Sunday for actor Kangana Ranaut as she started her day with horseback riding. Taking to Instagram, Kangana shared a video of her riding a horse in Mumbai. She can be seen sporting an orange polo shirt with black pants. “Today morning horseback riding,” she captioned the clip. Netizens are quite impressed to see Kangana’s horse-riding skills. “Very nice…you are so good at it,” a user commented. “Woah…awesome,” another one wrote. Kangana had learned horseback riding a few years ago. In fact, in the film ‘Manikarnika- The Queen of Jhansi’, she did her own stunts which involved horseback riding. Speaking of Kangana’s upcoming movie projects, she will be next seen in ‘Thalaivi’, which is based on Tamil Nadu’s former Chief Minister, Jayalalithaa. She also has ‘Tejas’ and ‘Dhaakad’ in her kitty. ‘Manikarnika Returns: The Legend Of Didda’ is also in pipeline.
Opinion8 months ago
South Block’s mistakes will now be corrected by Army
Sports11 months ago
When a bodybuilder breaks Shoaib’s record
News1 year ago
PM Modi must take governance back from babus
Spiritually Speaking10 months ago
Spiritual beings having a human experience
News12 months ago
Chinese general ordered attack on Indian troops: US intel report
Sports11 months ago
West Indies avoid follow-on, England increase lead to 219
Legally Speaking1 year ago
Law relating to grant, rejection and cancellation of bail
Royally Speaking9 months ago
The young royal dedicated to the heritage of Jaipur